Job added in hotlist
Applied job
Contract job
90-day-old-job
part-time-job
Recruiter job
Employer job
Expanded search
Apply online not available
View more jobs in Lexington, MA
View more jobs in Massachusetts

Job Details

Scientist Formulation Process Development

Location
Lexington, MA, United States

Posted on
Jun 29, 2020

Apply for this job






Profile

Description
**MEMBERS ONLY**SIGN UP NOW***. is a preclinical biotech that is on a mission to improve the lives of people suffering from serious life-altering diseases. **MEMBERS ONLY**SIGN UP NOW***. is developing transformative RNA therapies to treat diseases caused by the dysregulation of gene expression. Currently, we are developing new approaches to treat a wide range of diseases and access new targets not currently addressable by existing approaches and modalities.
Job Summary
We are seeking a highly motivated and scientifically rigorous individual to join the Research and Process Development team as a Scientist. The position will report to the Director of the group and
will focus on process development for drug products.
Job Responsibilities
Design and conduct experiments for advancing understanding and further developing drug product formulations
Scale up and characterize drug product processes
Analyze, interpret the results and plan future experiments based on the findings which will advance efforts of process development
Write batch records/protocols for manufacture of drug product
Write/review analytical method protocols/stability protocols
Characterize biophysical and physiochemical properties of drug product formulations
Further expand delivery capabilities for **MEMBERS ONLY**SIGN UP NOW***. and build our intellectual property estate
Prepare technical reports and presentations for clear communication of scientific findings across interdisciplinary teams
Required Skills & Qualifications
M.S./Ph.D. in Chemistry/Physical Chemistry/Chemical Engineering/Biochemistry
M.S. with 8-10 years or Ph.D. with 2-4 years of relevant experience in process development, tech transfer and working in manufacturing/production group.
Comprehensive know-how and direct experience of different pump systems, TFF, fluid flow and mixing dynamics in formulation processes is a must.
Experience with lipid nanoparticles (LNP) is required
Direct experience with messenger RNA encapsulation/quantification/characterization/handling is strongly preferred
Demonstrated success in development of formulation processes & characterization of drug products.
Experience handling nucleic acids preferred
Experience with biophysical characterization assays for delivery systems.
Working knowledge of Quality systems, GMP-related requirements, regulatory requirements for CMC and ICH guidelines is desirable
Strong disposition for analytics (QC, methods, assay development)
Works collaboratively within group as well as within interdisciplinary teams
Demonstrated experience in working with outside CROs/CMOs
Manages time effectively demonstrating ability to perform multiple projects at one time
Desire to work in a fast-paced environment
Excellent organizational and communication skills
Strong analytical and problem-solving skills
**MEMBERS ONLY**SIGN UP NOW***. is committed to equal employment opportunity. All applicants must have authorization to work in the U.S.
M.S./Ph.D. in Chemistry/Physical Chemistry/Chemical Engineering/Biochemistry
M.S. with 8-10 years or Ph.D. with 2-4 years of relevant experience in process development, tech transfer and working in manufacturing/production group.
Comprehensive know-how and direct experience of different pump systems, TFF, fluid flow and mixing dynamics in formulation processes is a must.
Experience with lipid nanoparticles (LNP) is required
Direct experience with messenger RNA encapsulation/quantification/characterization/handling is strongly preferred
Demonstrated success in development of formulation processes & characterization of drug products.
Experience handling nucleic acids preferred
Experience with biophysical characterization assays for delivery systems.
Working knowledge of Quality systems, GMP-related requirements, regulatory requirements for CMC and ICH guidelines is desirable
Strong disposition for analytics (QC, methods, assay development)
Works collaboratively within group as well as within interdisciplinary teams
Demonstrated experience in working with outside CROs/CMOs
Manages time effectively demonstrating ability to perform multiple projects at one time
Desire to work in a fast-paced environment
Excellent organizational and communication skills
Strong analytical and problem-solving skills
**MEMBERS ONLY**SIGN UP NOW***. is committed to equal employment opportunity. All applicants must have authorization to work in the U.S.

Company info

Sign Up Now - ChemistryCrossing.com

Similar Jobs:
Production Technician
Location : Marlborough, MA
Job Information DuPont Production Technician in Marlborough Massachusetts Production Technician (Job Number: 210743W-01) Description Electronics & Imaging is a technology leader with a unique depth and breadth of knowledge, applic...
Job Description:\nVertex is seeking a talented individual to join our Formulation Development group in Boston, MA. Formulation Development group is a fast paced and high energy environment. The successful candidate for this direct...
Manager Quality Control
Location : Lexington, MA
Job Description Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Quality Control Manager in our Lexington, MA office. At Takeda, we are transforming the ...