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Job Details

Mass Spectrometry Laboratory Manager

Company name

Rockville, MD

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Job Title: Mass Spectrometry Laboratory Manager

Department: Mass Spectrometry, Research & Development

Position Overview

The Mass Spectrometry Laboratory Manager is responsible for overseeing and maintaining LCMS system standards and processes, and troubleshooting LCMS instrumentations to the highest quality. The MS laboratory manager will allocate resources, identify areas for improving MS workflows by collaborating directly and consistently with Mass Spec team and other departments within the company, manage the relationship with application vendors, and maintain Mass Spec laboratory operations by providing trainings to group members, monitoring and assisting in instrument upkeep, coordinating various Mass Spec and/or R&D projects, and apprising stakeholders of progressions. The successful candidate will be highly motivated to work within a science focused, collaborative and multidisciplinary team environment to achieve the companys goal of providing solutions for precision medicine.

Essential Functions

  • Oversee the troubleshooting, maintenance, and basic repairing of instrumentation including Triple-Quadrupole, Quadrupole-Orbitrap and nano-LC in GLP/CLIA settings. Manage and provide suitable LCMS instrument trainings for the Mass Spec group; communicate with LCMS vendors for the upkeep of the instruments to ensure the highest quality of NantOmics targeted and discovery LCMS platforms. Plan, monitor and provide assistance for all aspects of activities in MS lab. (45%)

  • Plan and develop automatic real time LC-MS quality control monitoring platform. Establish electronic documentation system to record activities in the Mass Spec lab. Identify areas for improving the laboratory workflow and provide support to implement the improvements. Assist Mass Spec team in developing protocols and evaluating platforms and methods. (25%)

  • Coordinate and review research protocols and contracts of internal and external groups. Support Mass Spec team and other departments within the company to ensure projects are successfully implemented. (20%)

  • Develop and maintain standard operating procedures for maintenance of GLP/CLIA facility. (10%)

Qualification and Experience/Knowledge/Skills Requirements

  • BS or MS degree in Chemistry, Biochemistry, Biotechnology, or related discipline with 4-8 years/ Ph.D. in related discipline with 1-5 years post-doctoral hands-on experience with Quadrupole-Orbitrap, Triple-Quadrupole, and nano-LC. Strong background in mass spectrometry

  • Excellent LCMS troubleshooting skills; familiarity with peptide/protein assays development and optimization

  • Previous management experience and strong leadership skills essential

  • Ability to troubleshoot instrument issues under pressure

  • Strong and collaborative work ethic; must be able to work efficiently in a dynamic, fast paced environment where change is frequent and employees share many responsibilities

  • Self-starter must have strong written and oral communication and interpersonal skills. Effective and precise communicating cross-functionally in a timely and meaningful fashion

This position requires the employee to work in the laboratory which creates the potential for occupational exposure to biological or chemical hazards.

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