Job added in hotlist
Applied job
Contract job
90-day-old-job
part-time-job
Recruiter job
Employer job
Expanded search
Apply online not available
View more jobs in Boston, MA
View more jobs in Massachusetts

Job Details

Scientist Cell Product Clinical Translation

Company name
Takeda Pharmaceutical Company Limited.

Location
Boston, MA, United States

Employment Type
Full-Time

Industry
Sciences, Scientist, Chemistry, Engineering, Pharmaceutical

Posted on
Jun 21,2019

Valid Through
Oct 04,2019

Apply for this job






Profile

Job Description

Are you looking for a patient-focused company that will inspire you and support your career? If so, be empowered to take charge of your future at Takeda.  Join us as a Scientist, Cell Product Clinical Translation in our Cambridge office.

Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. As a Scientist working on the Cell Product Clinical Translation team, you will be empowered to provide scientific expertise and work with stakeholders across multiple functions at Takeda, and a typical day will include: 

POSITION OBJECTIVES:

The Cell Product Clinical Translation team is uniquely positioned to link CMC and clinical CART biomarkers to investigate correlatives associated with cell product efficacy and safety in oncology indications. This position’s primary role is to provide scientific expertise and project leadership in integrating cross-functional biomarker data from multiple platforms and line functions to investigate safety, efficacy and mechanisms of resistance and relapse in cell therapies. In this unique role you will be at the scientific forefront of cell therapies striving towards improving outcomes for patients with B cell malignancies and solid tumors through in-depth product characterization and establishing biomarker strategies.

POSITION ACCOUNTABILITIES:

Investigates mode of action (MoA), critical quality attributes (CQA) and mechanisms of resistance and relapse in cell therapies through collaboration and integration of biomarker data from process development, manufacturing (CMC), product characterization, animal models, tumor microenvironment, clinical biomarkers, pharmacology, safety and efficacy.

Represents functional area on GCT project teams by communicating activities from designated functional area to project team

Prepares study protocols, reports, technology transfer documentation, and regulatory documents for clinical trials. 

Understands project timelines and deliverables and plans/coordinates project work accordingly with departmental, functional and external stakeholders

Reviews, interprets and communicates data cross-functionally within CMC and/or project teams.

Supports local and global initiatives which may include leading initiatives or work streams

EDUCATION, EXPERIENCE, BEHAVIOURAL COMPETENCIES AND SKILLS:

Education and Experience:

Required:

Bachelors degree in chemistry, biology, pharmacy, engineering or related pharmaceutical science and 8 years relevant industry experience

Masters degree in chemistry, biology, pharmacy, engineering or related pharmaceutical science; 6 years relevant industry experience

PhD in chemistry, biology, pharmacy, chemical or biomedical engineering or related pharmaceutical science; 0 years relevant industry experience

Experience in CART, immunology, immune-oncology, vaccines or virology with strong understanding of solid tumor or B cell malignancies

In-depth knowledge of various mechanisms of therapeutic response and resistance mechanisms utilizing in vitro, in vivo or ex vivo patient-derived models

Understanding of current therapeutic and combination therapy landscape, including immune-checkpoint blockade, in cancer immunotherapy

Experience with immune-phenotyping by FACS (flow cytometry), primary cell culture, immunofluorescence, ELISA, and PCR

A track record of independent critical thinking and scientific achievement demonstrated by national presentations and publications

Prior experience with translational aspects of IND, NDA or BLA desirable

Knowledge and Skills:

Analytical and Problem Solving Skills - Able to troubleshoot critical issues or problems using appropriate information and, determine causes and possible solutions

Teamwork -- Ability to work well on global cross-functional teams.

Communication Skills -Able to expresses one’s self clearly and concisely within team; documents issues and/or concerns concisely with colleagues; adjusts communication style as appropriate for the audience; timely and effectively communicates with  senior management; technical writing skills to support authorship and approval of internal technical documents

Organization – Exercises good time management and prioritization skills to balance multiple project and departmental objectives

Technical - Subject matter expertise in a specific scientific area or areas. Demonstrated ability to successfully contribute across multiple scientific endeavors

Knowledge Sharing - Ability to capture knowledge within the organization; improves solutions, processes, and deliverables through use of information; improves information capital by contributing experience, theories, deliverables, and models for others to use

Resource Management -Project management skills; ability to manage one’s time within individual, departmental, and corporate goals and timelines; management of internal external resources (vendors)

External Involvement – Demonstrated involvement in professional community evidenced by presentation of scientific posters or lectures at professional conferences or events. Interacts with external vendors for projects

Leadership Skills – Develops and uses knowledge and interpersonal skills to appropriately influence and guide others towards the accomplishment of department/function goals and objectives.

TRAVEL REQUIREMENTS:

May require approximately 10% travel

WHAT TAKEDA CAN OFFER YOU:

401(k) with company match and Annual Retirement Contribution Plan

Tuition reimbursement

Company match of charitable contributions

Health & Wellness programs including onsite flu shots and health screenings

Generous time off for vacation and the option to purchase additional vacation days

Community Outreach Programs

Empowering Our People to Shine

Learn more at takedajobs.com

No Phone Calls or Recruiters Please.

#LI-PW1

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job ID

R0009790

Company info

Takeda Pharmaceutical Company Limited.
Website : https://www.takeda.com

Company Profile
As a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Takeda Pharmaceuticals U.S.A., Inc. (TPUSA) is among the top 15 pharmaceutical companies in the United States. TPUSA was founded in 1998 to accelerate Takeda's global expansion into the U.S. market. Takeda's U.S. clinical development activities are conducted via Takeda Development Center Americas, Inc., which has a robust pipeline of compounds in multiple therapeutic areas including metabolic and cardiovascular diseases, central nervous system, respiratory and immunology, oncology and general medicine. Striving toward better health is at the center of everything we do. Takeda is enjoying tremendous growth as an emerging global leader in the pharmaceutical industry, but remains ever mindful of our commitment to serve people worldwide by striving toward better health through leading innovation in medicine.The spirit of our commitment extends to our employees, partners and the larger community.

Similar Jobs:
Associate Research Chemist
Location : Andover, MA
Rapiscan Systems is an industry leader in detection technology, providing cargo and vehicle inspection systems and services for ports, borders, military, high-threat facilities, and checkpoints to help customers combat terrorism, ...
Description Who are we? Acceleron is a clinical-stage biopharmaceutical company dedicated to the discovery, development, and commercialization of therapeutics to treat serious and rare diseases. The Companys leadership in the unde...
VP of Chemistry
Location : Cambridge, MA
Job Location: Cambridge, MA Location: US-MA-Cambridge ID: 2018-1117 # of Openings : 1 Category: Research & Development Address: 650 East Kendall Street Overview Deerfield Management is an investment management firm committed to im...